Tenover JS. Effects of testosterone supplementation in the aging male. Amory JK, Watts NB, Easley KA, Sutton PR, Anawalt BD, Matsumoto AM, Bremner WJ, Tenover JL depression. Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone. Basurto L, Zarate A, Gomez R, Vargas C, Saucedo R, Galvan R. Effect of testosterone therapy on lumbar spine and hip mineral density in elderly men. Anderson FH, Francis RM, Faulkner K. Androgen supplementation in eugonadal men with osteoporosis-effects of 6 months of treatment on bone mineral density and cardiovascular risk factors.
Rabiee A, Dwyer AA, Caronia LM, Hayes FJ, Yialamas MA, Andersen DK, Thomas B, Torriani M, Elahi D. Impact of acute biochemical castration on insulin sensitivity in healthy adult men. Waldkirch E, Uckert S, Schultheiss D, Geismar U, Bruns C, Scheller F, Jonas U, Becker AJ, Stief CG, Hedlund P. Non-genomic effects of androgens on isolated human vascular and nonvascular penile erectile tissue. Behre HM, Bohmeyer J, Nieschlag E. Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls. Giltay EJ, Tishova YA, Mskhalaya GJ, Gooren LJ, Saad F, Kalinchenko SY. Effects of testosterone supplementation on depressive symptoms and sexual dysfunction in hypogonadal men with the metabolic syndrome. Perry PJ, Yates WR, Williams RD, Andersen AE, MacIndoe JH, Lund BC, Holman TL. Testosterone therapy in late-life major depression in males.
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Tracz MJ, Sideras K, Bolona ER, Haddad RM, Kennedy CC, Uraga MV, Caples SM, Erwin PJ, Montori VM. Testosterone use in men and its effects on bone health. A systematic review and meta-analysis of randomized placebo-controlled trials. Isidori AM, Greco EA, Aversa A. Androgen deficiency and hormone-replacement therapy.
Additionally, testosterone therapy may worsen sleep apnea in older people. Prescription testosterone treatments are available as gels, skin patches, and intramuscular injections. Testosterone levels naturally rise in response to sexual arousal and activity.
Nieschlag E, Buchter D, Von Eckardstein S, Abshagen K, Simoni M, Behre HM. Repeated intramuscular injections of testosterone undecanoate for substitution therapy in hypogonadal men. Jockenhovel F, Minnemann T, Schubert M, Freude S, Hubler D, Schumann C, Christoph A, Gooren L, Ernst M. Timetable of effects of testosterone administration to hypogonadal men on variables of sex and mood. Zitzmann M, Erren M, Kamischke A, Simoni M, Nieschlag E. Endogenous progesterone and the exogenous progestin norethisterone enanthate are associated with a proinflammatory profile in healthy men. Yialamas MA, Dwyer AA, Hanley E, Lee H, Pitteloud N, Hayes FJ. Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism. Haider A, Gooren LJ, Padungtod P, Saad F. Improvement of the metabolic syndrome and of non-alcoholic liver steatosis upon treatment of hypogonadal elderly men with parenteral testosterone undecanoate.
- On average, obese men have 30% lower testosterone levels than those who are normal-weight .
- Lack of GRH leads to lower levels of luteinizing hormone, which in turn reduces the production of testosterone .
- Second, high aromatase and estrogen activity reduces the production of gonadotropin-releasing hormone .
- One of its most important functions in both genders is to maintain muscle mass and promote muscle growth and bone strength.
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Men with higher levels of testosterone usually have greater sexual activity. Older men need more testosterone for libido and erectile function.
They are the glands where sperm and testosterone are produced. Australia’s National Health and Medical Research Council supported the study. Bayer Pharma AG provided testosterone, placebo and financial support but was not directly involved in the study. Saylor PJ, Smith MR. Metabolic complications of androgen deprivation therapy for prostate cancer. Saad F, Gooren LJ, Haider A, Yassin A. A dose–response study of testosterone on sexual dysfunction and features of the metabolic syndrome using testosterone gel and parenteral testosterone undecanoate.
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But it’s important to note that erectile dysfunction is often due to other conditions or medications rather than low testosterone levels. The testes are the most essential organs of the male reproductive system.